Histidine can be used to treat anxiety, but it’s anti-anxiety properties are little known and little understood. It is thought that histidine lessens beta waves and encourages alpha waves which promote relaxation. It can also improve digestion and often a calmer stomach equals a calmer mind and less anxiety. Histidine can also help with the sexual dysfunction that many anxiety sufferers have.
If you take too much Histidine you may suffer from more anxiety and not less, including palpitations and panic attacks.And that’s the annoying thing about a lot of amino acids: it’s hard to be sure at what dose they will be effective and how much is too much. There are still no reliable tests to show deficiency, so you have to go by symptoms. But differing amino acid deficiencies can have similar symptoms.
If you want to try histidine, then start on a low dose and increase it very gradually to see if you have any success. Don’t mix it with any other medication either from a prescription or over the counter as it can increase histamine levels and cause a worsening of side-effects.